ST5 Antikörper (Internal Region)
Kurzübersicht für ST5 Antikörper (Internal Region) (ABIN6257500)
Target
Alle ST5 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
 - Internal Region
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Spezifität
 - ST5 Antibody detects endogenous levels of total ST5.
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Homologie
 - Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
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Aufreinigung
 - The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogen
 - A synthesized peptide derived from human ST5, corresponding to a region within the internal amino acids.
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Isotyp
 - IgG
 
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Applikationshinweise
 - WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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Beschränkungen
 - Nur für Forschungszwecke einsetzbar
 
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Format
 - Liquid
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Konzentration
 - 1 mg/mL
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Buffer
 - Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
 - Sodium azide
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Vorsichtsmaßnahmen
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
 - -20 °C
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Informationen zur Lagerung
 - Store at -20 °C. Stable for 12 months from date of receipt.
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Haltbarkeit
 - 12 months
 
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- ST5 (Suppression of Tumorigenicity 5 (ST5))
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Andere Bezeichnung
 - ST5
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Hintergrund
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Description: Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May be involved in cytoskeletal organization and tumorogenicity. Isoform 1 seems to be involved in a signaling transduction pathway leading to activation of MAPK1/ERK2. Isoform 3 may block ERK2 activation stimulated by ABL1. Isoform 3 may alter cell morphology and cell growth.
Gene: ST5
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Molekulargewicht
 - 126 kDa
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Gen-ID
 - 6764
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UniProt
 - P78524
 
Target
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