RIN1 Antikörper (C-Term)

Produktnummer ABIN6257477

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RIN1 in WB, ELISA, IF und ICC. Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus.

Kurzübersicht für RIN1 Antikörper (C-Term) (ABIN6257477)

Target: RIN1 (Ras and Rab Interactor 1 (RIN1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RIN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-RIN1 Antikörper

Bindungsspezifität: C-Term

Spezifität: RIN1 Antibody detects endogenous levels of total RIN1.

Homologie: Pig,Horse,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human RIN1, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu RIN1

Target: RIN1 (Ras and Rab Interactor 1 (RIN1))

Andere Bezeichnung: RIN1

Hintergrund:

Description: Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.

Gene: RIN1

Molekulargewicht: 84 kDa

Gen-ID: 9610

UniProt: Q13671