RNF125 Antikörper (Internal Region)
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- Target Alle RNF125 Antikörper anzeigen
- RNF125 (Ring Finger Protein 125 (RNF125))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RNF125 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- RNF125 Antibody detects endogenous levels of total RNF125.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human RNF125, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product RNF125 Primärantikörper
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anti-Ring Finger Protein 125 (RNF125) (AA 143-231) antibody
RNF125 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 1D3 unconjugated
anti-Ring Finger Protein 125 (RNF125) (AA 1-232) antibodyRNF125 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Ring Finger Protein 125 (RNF125) (C-Term) antibodyVerified RNF125 Reaktivität: Human ELISA, IF, FACS Wirt: Ziege Polyclonal unconjugated
anti-Ring Finger Protein 125 (RNF125) (AA 143-231) antibodyRNF125 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Ring Finger Protein 125 (RNF125) antibodyRNF125 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Ring Finger Protein 125 (RNF125) (AA 143-231) antibodyRNF125 Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-Ring Finger Protein 125 (RNF125) antibodyRNF125 Reaktivität: Human IF Wirt: Kaninchen Polyclonal unconjugated
anti-Ring Finger Protein 125 (RNF125) antibodyRNF125 Reaktivität: Maus WB Wirt: Kaninchen Polyclonal unconjugated
anti-Ring Finger Protein 125 (RNF125) (AA 1-105) antibodyRNF125 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Ring Finger Protein 125 (RNF125) (C-Term) antibodyRNF125 Reaktivität: Human, Maus, Ratte, Affe, Rind (Kuh), Meerschweinchen, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- RNF125 (Ring Finger Protein 125 (RNF125))
- Andere Bezeichnung
- RNF125 (RNF125 Produkte)
- Synonyme
- 4930553F04Rik antikoerper, TRAC-1 antikoerper, TRAC1 antikoerper, ring finger protein 125 antikoerper, RNF125 antikoerper, Rnf125 antikoerper
- Hintergrund
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Description: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins, such as DDX58/RIG-I, MAVS/IPS1, IFIH1/MDA5, JAK1 and p53/TP53 (PubMed:15843525, PubMed:17460044, PubMed:17643463, PubMed:26027934, PubMed:26471729, PubMed:25591766, PubMed:27411375). Acts as a negative regulator of type I interferon production by mediating ubiquitination of DDX58/RIG-I at 'Lys-181', leading to DDX58/RIG-I degradation (PubMed:17460044, PubMed:26471729). Mediates ubiquitination and subsequent degradation of p53/TP53 (PubMed:25591766). Mediates ubiquitination and subsequent degradation of JAK1 (PubMed:26027934). Acts as a positive regulator of T-cell activation (PubMed:15843525).
Gene: RNF125
- Molekulargewicht
- 26 kDa
- Gen-ID
- 54941
- UniProt
- Q96EQ8
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