RIOK2 Antikörper (Internal Region)

Produktnummer ABIN6257460

Der Kaninchen-Polyklonal Anti-RIOK2-Antikörper wurde für WB, ELISA, IF, IHC und ICC validiert. Er ist geeignet zum Nachweis von RIOK2 in Proben aus Human. }

Kurzübersicht für RIOK2 Antikörper (Internal Region) (ABIN6257460)

Target: RIOK2 (RIO Kinase 2 (RIOK2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RIOK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Produktdetails anti-RIOK2 Antikörper

Bindungsspezifität: Internal Region

Spezifität: RIOK2 Antibody detects endogenous levels of total RIOK2.

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human RIOK2, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu RIOK2

Target: RIOK2 (RIO Kinase 2 (RIOK2))

Andere Bezeichnung: RIOK2

Hintergrund:

Description: Serine/threonine-protein kinase involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in export of the 40S pre-ribosome particles (pre-40S) from the nucleus to the cytoplasm. Its kinase activity is required for the release of NOB1, PNO1 and LTV1 from the late pre-40S and the processing of 18S-E pre-rRNA to the mature 18S rRNA (PubMed:19564402). Regulates the timing of the metaphase-anaphase transition during mitotic progression, and its phosphorylation, most likely by PLK1, regulates this function (PubMed:21880710).

Gene: RIOK2

Molekulargewicht: 63 kDa

Gen-ID: 55781

UniProt: Q9BVS4