PLCE1 Antikörper

Produktnummer ABIN6257434

Produktdetails anti-PLCE1 Antikörper

Target: PLCE1 (Phospholipase C, epsilon 1 (PLCE1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLCE1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Spezifität: PLCE1 antibody detects endogenous levels of total PLCE1

Kreuzreaktivität: Human, Maus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Details zu PLCE1

Target: PLCE1 (Phospholipase C, epsilon 1 (PLCE1))

Andere Bezeichnung: PLCE1 (PLCE1 Produkte)

Synonyme: PLCE1 antikoerper, NPHS3 antikoerper, PLCE antikoerper, PPLC antikoerper, 4933403A21Rik antikoerper, PLCepsilon antikoerper, Plce antikoerper, mKIAA1516 antikoerper, phospholipase C, epsilon 1 antikoerper, phospholipase C epsilon 1 antikoerper, PLCE1 antikoerper, plce1 antikoerper, Plce1 antikoerper

Hintergrund:

Description: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. PLCE1 is a bifunctional enzyme which also regulates small GTPases of the Ras superfamily through its Ras guanine-exchange factor (RasGEF) activity. As an effector of heterotrimeric and small G-protein, it may play a role in cell survival, cell growth, actin organization and T-cell activation.

Gene: PLCE1

Gen-ID: 51196

UniProt: Q9P212

Pathways: EGFR Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling