MDFI Antikörper (Internal Region)

Produktnummer ABIN6257357

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MDFI in WB, ELISA, IHC, IF und ICC. Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus.

Kurzübersicht für MDFI Antikörper (Internal Region) (ABIN6257357)

Target: MDFI (MyoD Family Inhibitor (MDFI))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MDFI Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-MDFI Antikörper

Bindungsspezifität: Internal Region

Spezifität: MDFI Antibody detects endogenous levels of total MDFI.

Homologie: Pig,Bovine,Horse,Sheep,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MDFI, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu MDFI

Target: MDFI (MyoD Family Inhibitor (MDFI))

Andere Bezeichnung: MDFI

Hintergrund:

Description: Inhibits the transactivation activity of the Myod family of myogenic factors and represses myogenesis. Acts by associating with Myod family members and retaining them in the cytoplasm by masking their nuclear localization signals. Can also interfere with the DNA-binding activity of Myod family members. Plays an important role in trophoblast and chondrogenic differentiation. Regulates the transcriptional activity of TCF7L1/TCF3 by interacting directly with TCF7L1/TCF3 and preventing it from binding DNA. Binds to the axin complex, resulting in an increase in the level of free beta-catenin. Affects axin regulation of the WNT and JNK signaling pathways (By similarity).

Gene: MDFI

Molekulargewicht: 25 kDa

Gen-ID: 4188

UniProt: Q99750

Pathways: Maintenance of Protein Location