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MYO9B Antikörper (N-Term)

MYO9B Reaktivität: Human, Maus, Ratte WB, ELISA, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6257337
  • Target Alle MYO9B Antikörper anzeigen
    MYO9B (Myosin IXB (MYO9B))
    Bindungsspezifität
    • 2
    • 1
    • 1
    N-Term
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 11
    • 1
    Kaninchen
    Klonalität
    • 12
    Polyklonal
    Konjugat
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MYO9B Antikörper ist unkonjugiert
    Applikation
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Spezifität
    MYO9B Antibody detects endogenous levels of total MYO9B.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human MYO9B, corresponding to a region within N-terminal amino acids.
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    MYO9B (Myosin IXB (MYO9B))
    Andere Bezeichnung
    MYO9B (MYO9B Produkte)
    Synonyme
    CELIAC4 antikoerper, MYR5 antikoerper, MYO9B antikoerper, fb53f01 antikoerper, wu:fb53f01 antikoerper, wu:fc47c07 antikoerper, si:dkeyp-66d1.8 antikoerper, myosin IXB antikoerper, myosin IXb antikoerper, unconventional myosin-IXb antikoerper, MYO9B antikoerper, Myo9b antikoerper, myo9b antikoerper, LOC100450445 antikoerper
    Hintergrund

    Description: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Binds actin with high affinity both in the absence and presence of ATP and its mechanochemical activity is inhibited by calcium ions (PubMed:9490638). Also acts as a GTPase activator for RHOA (PubMed:9490638, PubMed:26529257). Plays a role in the regulation of cell migration via its role as RHOA GTPase activator. This is regulated by its interaction with the SLIT2 receptor ROBO1, interaction with ROBO1 impairs interaction with RHOA and subsequent activation of RHOA GTPase activity, and thereby leads to increased levels of active, GTP-bound RHOA (PubMed:26529257).

    Gene: MYO9B

    Molekulargewicht
    250 kDa
    Gen-ID
    4650
    UniProt
    Q13459
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