MAGEC2 Antikörper (Internal Region)

Produktnummer ABIN6257317

Produktdetails anti-MAGEC2 Antikörper

Target: MAGEC2 (Melanoma Antigen Family C, 2 (MAGEC2))

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAGEC2 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: MAGEC2 Antibody detects endogenous levels of total MAGEC2.

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MAGEC2, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu MAGEC2

Target: MAGEC2 (Melanoma Antigen Family C, 2 (MAGEC2))

Andere Bezeichnung: MAGEC2 (MAGEC2 Produkte)

Synonyme: CT10 antikoerper, HCA587 antikoerper, MAGEE1 antikoerper, MAGEC2 antikoerper, MAGE family member C2 antikoerper, melanoma antigen family C, 2 antikoerper, MAGEC2 antikoerper, Magec2 antikoerper

Hintergrund:

Description: Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes (E2) at the E3:substrate complex.

Gene: MAGEC2

Molekulargewicht: 41 kDa

Gen-ID: 51438

UniProt: Q9UBF1