ADCY6 Antikörper (Internal Region)
Kurzübersicht für ADCY6 Antikörper (Internal Region) (ABIN6257031)
Target
Alle ADCY6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Internal Region
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Spezifität
- ADCY5/6 Antibody detects endogenous levels of total ADCY5/6.
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Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
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Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogen
- A synthesized peptide derived from human ADCY5/6, corresponding to a region within the internal amino acids.
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
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Haltbarkeit
- 12 months
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- ADCY6 (Adenylate Cyclase 6 (ADCY6))
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Andere Bezeichnung
- ADCY5,ADCY6
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Hintergrund
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Description: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling (PubMed:15385642, PubMed:26206488, PubMed:24700542). Mediates signaling downstream of ADRB1 (PubMed:24700542). Regulates the increase of free cytosolic Ca2+ in response to increased blood glucose levels and contributes to the regulation of Ca2+-dependent insulin secretion (PubMed:24740569).
Gene: ADCY5
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Molekulargewicht
- 138 kDa
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Gen-ID
- 111, 112
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UniProt
- O95622, O43306
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Pathways
- EGFR Signaling Pathway, Neurotrophin Signalübertragung, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
Target
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