Tumor Protein p73 Antikörper (pTyr99)
Kurzübersicht für Tumor Protein p73 Antikörper (pTyr99) (ABIN6256817)
Target
Alle Tumor Protein p73 (TP73) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pTyr99
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Spezifität
- Phospho-p73 (Tyr99) Antibody detects endogenous levels of p73 only when phosphorylated at Tyrosine 99.
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Homologie
- Pig,Bovine,Sheep,Dog,Chicken
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Aufreinigung
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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Immunogen
- A synthesized peptide derived from human p73 around the phosphorylation site of Tyr99.
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:1000, ELISA(peptide) 1:20000-1:40000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
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Haltbarkeit
- 12 months
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- Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))
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Andere Bezeichnung
- TP73
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Hintergrund
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Description: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
Gene: TP73
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Molekulargewicht
- 80kDa
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Gen-ID
- 7161
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UniProt
- O15350
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Pathways
- Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus
Target
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