Histone H2A Antikörper (pThr121)

Produktnummer ABIN6256470

Der Kaninchen Polyklonal Anti-Histone H2A-Antikörper wurde für WB, IHC und ELISA validiert. Er ist geeignet, Histone H2A in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für Histone H2A Antikörper (pThr121) (ABIN6256470)

Target: Histone H2A

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Histone H2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-Histone H2A Antikörper

Bindungsspezifität: pThr121

Spezifität: Phospho-Histone H2A (Thr121) Antibody detects endogenous levels of Histone H2A only when phosphorylated at Threonine 121

Kreuzreaktivität: Human, Maus, Ratte (Rattus)

Aufreinigung: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogen: A synthesized peptide derived from human Histone H2A around the phosphorylation site of Threonine 121

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200 WB 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C.Stable for 12 months from date of receipt

Haltbarkeit: 12 months

Details zu Histone H2A

Target: Histone H2A

Hintergrund:

Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Gene: HIST1H2AG, HIST1H2AI, HIST1H2AK, HIST1H2AL, HIST1H2AM

Molekulargewicht: 15kDa

Gen-ID: 83, 298, 330

UniProt: P0C0S8, P04908, P20671, Q96KK5, Q6FI13, Q7L7L0