Aryl Hydrocarbon Receptor Antikörper (pSer36)

Produktnummer ABIN6256291

Dieses Anti-Aryl Hydrocarbon Receptor-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Aryl Hydrocarbon Receptor in WB, IHC, ELISA, IF und ICC. Geeignet für Human, Maus und Ratte.

Kurzübersicht für Aryl Hydrocarbon Receptor Antikörper (pSer36) (ABIN6256291)

Target: Aryl Hydrocarbon Receptor (AHR)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Aryl Hydrocarbon Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-Aryl Hydrocarbon Receptor Antikörper

Bindungsspezifität: pSer36

Spezifität: Phospho-AhR (Ser36) Antibody detects endogenous levels of AhR only when phosphorylated at Serine 36

Kreuzreaktivität: Human, Maus, Ratte (Rattus)

Aufreinigung: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogen: A synthesized peptide derived from human AhR around the phosphorylation site of Serine 36

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C.Stable for 12 months from date of receipt

Haltbarkeit: 12 months

Details zu Aryl Hydrocarbon Receptor

Target: Aryl Hydrocarbon Receptor (AHR)

Andere Bezeichnung: AhR

Hintergrund:

Description: Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1.

Gene: AHR

Molekulargewicht: 90kDa

Gen-ID: 196

UniProt: P35869, A9YTQ3

Pathways: Regulation of Cell Size