RYR2 Antikörper (pSer2814)
Kurzübersicht für RYR2 Antikörper (pSer2814) (ABIN6256236)
Target
Alle RYR2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer2814
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Spezifität
- Phospho-RYR2( Ser2814) Antibody detects endogenous levels of RYR2.
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Kreuzreaktivität
- Hund, Human
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Aufreinigung
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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Immunogen
- A synthesized peptide derived from human RYR2 around the phosphorylation site of Ser2814.
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Isotyp
- IgG
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anti-Ryanodine Receptor 2 (Cardiac) (RYR2) (AA 901-1192) antibody
RYR2 Reaktivität: Human IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Ryanodine Receptor 2 (Cardiac) (RYR2) (AA 4850-4950) antibodyRYR2 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Ryanodine Receptor 2 (Cardiac) (RYR2) (AA 1489-1502), (Intracellular), (N-Term) antibodyRYR2 Reaktivität: Human IHC, WB, IF, IC Wirt: Kaninchen Polyclonal unconjugated
anti-Ryanodine Receptor 2 (Cardiac) (RYR2) (pSer2808) antibodyRYR2 Reaktivität: Human, Maus, Ratte, Kaninchen IHC, WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Ryanodine Receptor 2 (Cardiac) (RYR2) antibodyRYR2 Reaktivität: Human, Maus, Ratte ELISA, WB, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Ryanodine Receptor 2 (Cardiac) (RYR2) antibodyRYR2 Reaktivität: Human, Maus, Ratte IHC, ELISA, WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Ryanodine Receptor 2 (Cardiac) (RYR2) (Tyr1018) antibodyRYR2 Reaktivität: Human, Maus, Ratte IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
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Haltbarkeit
- 12 months
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- RYR2 (Ryanodine Receptor 2 (Cardiac) (RYR2))
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Andere Bezeichnung
- RYR2
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Hintergrund
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Description: Calcium channel that mediates the release of Ca2+ from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca2+ levels due to activation of the L-type calcium channel CACNA1C. The calcium channel activity is modulated by formation of heterotetramers with RYR3. Required for cellular calcium ion homeostasis. Required for embryonic heart development.
Gene: RYR2
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Molekulargewicht
- 564 kDa
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Gen-ID
- 6262
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UniProt
- Q92736
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Pathways
- Myometrial Relaxation and Contraction
Target
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