tau Antikörper (pSer199)
Kurzübersicht für tau Antikörper (pSer199) (ABIN6256183)
Target
Alle tau Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- pSer199
-
Spezifität
- Phospho-Tau (Ser199) Antibody detects endogenous levels of Tau.
-
Kreuzreaktivität
- Human, Maus, Ratte (Rattus)
-
Aufreinigung
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
-
Immunogen
- A synthesized peptide derived from human Tau around the phosphorylation site of Ser199.
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
-
Haltbarkeit
- 12 months
-
-
- tau (tau Protein)
-
Andere Bezeichnung
- Tau
-
Hintergrund
-
Description: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Gene: MAPT
-
Molekulargewicht
- 50-80kDa
-
Gen-ID
- 4137
-
UniProt
- P10636
Target
-