SOX9 Antikörper (pSer181)
Kurzübersicht für SOX9 Antikörper (pSer181) (ABIN6255043)
Target
Alle SOX9 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer181
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Spezifität
- Phospho-SOX9 (Ser181) Antibody detects endogenous levels of SOX9 only when phosphorylated at Serine 181.
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Homologie
- Pig,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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Aufreinigung
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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Immunogen
- A synthesized peptide derived from human SOX9 around the phosphorylation site of Ser181.
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
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Haltbarkeit
- 12 months
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- SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))
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Andere Bezeichnung
- SOX9
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Hintergrund
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Description: Transcriptional regulator (PubMed:24038782). Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219 (By similarity). Plays a role in chondrocyte differentiation (By similarity). Important for normal skeletal development (PubMed:24038782).
Gene: SOX9
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Molekulargewicht
- 69kDa
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Gen-ID
- 6662
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UniProt
- P48436
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Pathways
- EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
Target
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