Histone 3 Antikörper (H3K18ac)
Kurzübersicht für Histone 3 Antikörper (H3K18ac) (ABIN6254860)
Target
Alle Histone 3 (H3) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- H3K18ac
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Spezifität
- Acetyl-Histone H3 (Lys18) Antibody detects endogenous levels of total Histone H3 protein only when acetylated at lysine18.
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Kreuzreaktivität
- Human, Maus, Ratte (Rattus)
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Aufreinigung
- affinity purification
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Immunogen
- The antiserum was produced against synthesized peptide derived from human Histone H3 around the acetylated site of Lys18.
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500~1:2000 IHC: 1:50~1:200 IF 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4,50 % glycerol.
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- Histone 3 (H3) (Histone H3 (H3))
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Andere Bezeichnung
- Histone H3
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Hintergrund
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Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Gene: HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J
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Molekulargewicht
- 15 kDa
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Gen-ID
- 8, 350, 835
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UniProt
- P68431, Q71DI3, P84243
Target
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