Ataxin 3 Antikörper (AA 120-250)

Produktnummer ABIN6254159

Der Ziege Polyklonal anti-Ataxin 3 Antikörper wird verwendet zum Nachweis von Ataxin 3 in Proben von Human, Maus, Ratte, Rind (Kuh), Schaf, Pferd, Kaninchen, Meerschweinchen, Hund, Affe, Schwein, Cat, Huhn, Esel, Ziege, Hamster und Avian. Er wurde validiert für WB.

Kurzübersicht für Ataxin 3 Antikörper (AA 120-250) (ABIN6254159)

Target: Ataxin 3 (ATXN3)

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schaf, Pferd, Kaninchen, Meerschweinchen, Hund, Affe, Schwein, Cat, Huhn, Esel, Ziege, Hamster, Avian

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser Ataxin 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Ataxin 3 Antikörper

Bindungsspezifität: AA 120-250

Verwendungszweck: Anti-ATXN3

Sequenz: KEHWFTVRKL GKQWFNLNSL LTGPELISDT YLALFLAQLQ QEGYSIFVVK GDLPDCEADQ LLQMIRVQQM HRPKLIGEEL AQLKEQRVHK TDLERVLEAN DGSGMLDEDE EDLQRALALS RQEIDMEDEE ADL

Spezifität: Detects levels of ATXN3 protein in transfected cells with GFP-ATXN3 and endogenous levels in U118, SH-SY5Y, At-T20 and hTERT cell lysates by Western blot. This Ab is similar to AB0089.

Produktmerkmale: Ataxin 3

Aufreinigung: Epitope affinity purified

Immunogen: Purified recombinant peptide derived from within residues 120 aa to 250 aa of human ATXN3 produced in E. coli.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:250-1:2,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: preservatives. Glycerol and azide FREE.

Konservierungsmittel: Azide free

Handhabung: The antibody solution should be gently mixed before use.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.

Details zu Ataxin 3

Target: Ataxin 3 (ATXN3)

Andere Bezeichnung: ATXN3

Hintergrund:

Goat polyclonal antibody to ATXN3. This protein appears to be a component of the ubiquitin proteasome system and has deubiquitinase activity. It may also have roles in neuroprotection, protein homeostasis maintenance, transcriptional and cytoskeleton regulation, myogenesis and degradation of misfolded chaperone substrates. The protein contains Qn repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease also known as spinocerebellar ataxia-3, an autosomal dominant neurologic disorder.

AT3, ATX3, ataxin-3, ataxin 3 variant h, autosomal dominant ataxin 3, ataxin 3 variant m, ataxin 3 variant ref, JOS, josephin, Machado-Joseph, Machado-Joseph disease protein 1, MJD, MJD1, SCA3, spinocerebellar ataxia 3, olivopontocerebellar ataxia 3, spinocerebellar ataxia type 3 protein antibody.