CD163 Antikörper (PE)
-
- Target Alle CD163 Antikörper anzeigen
- CD163
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser CD163 Antikörper ist konjugiert mit PE
-
Applikation
- Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC), Fluorescence Microscopy (FM)
- Spezifität
- The CD163 antigen is the cysteine-rich human scavenger receptor protein (p155, M130) found on mononuclear phagocytes, monocytes, and macrophages. CD163 is up-regulated on mononuclear phagocytes by IL-4, IL-6 and dexamethasone and serves as a receptor for the hemoglobin / haptoglobin complex. Expression of CD163 is restricted to cells of monocyte lineage and increases as the monocytes mature into macrophages. CD163 is present on all CD14 + monocytes, most CD64+ monocytes, and demonstrates higher expression on CD16+ monocytes. Stimulation of monocytes and macrophages by lipopolysacharide (LPS), IL-10, and tumor necrosis factor alpha (TNF-α) causes shedding of CD163 from the cell surface into plasma or supernata
- Klon
- MAC2-158
- Isotyp
- IgG1
- Top Product
- Discover our top product CD163 Primärantikörper
-
-
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Lagerung
- 4 °C
-
- Target
- CD163
- Andere Bezeichnung
- CD163 (CD163 Produkte)
- Hintergrund
- Antigen distribution: The CD163 antigen is the cysteine-rich human scavenger receptor protein (p155, M130) found on mononuclear phagocytes, monocytes, and macrophages. CD163 is up-regulated on mononuclear phagocytes by IL-4, IL-6 and dexamethasone and serves as a receptor for the hemoglobin / haptoglobin complex. Expression of CD163 is restricted to cells of monocyte lineage and increases as the monocytes mature into macrophages. CD163 is present on all CD14 + monocytes, most CD64+ monocytes, and demonstrates higher expression on CD16+ monocytes. Stimulation of monocytes and macrophages by lipopolysacharide (LPS), IL-10, and tumor necrosis factor alpha (TNF-α) causes shedding of CD163 from the cell surface into plasma or supernata. Cellular Expression: Mononuclear phagocytes, monocytes and macrophages.
-