CD163 Antikörper (PE)

Produktnummer ABIN6253945

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD163 in WB, FACS, ELISA, ICC und FM. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CD163 Antikörper (PE) (ABIN6253945)

Target: CD163

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD163 Antikörper ist konjugiert mit PE

Applikation: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC), Fluorescence Microscopy (FM)

Klon: MAC2-158

Produktdetails anti-CD163 Antikörper (PE)

Spezifität: The CD163 antigen is the cysteine-rich human scavenger receptor protein (p155, M130) found on mononuclear phagocytes, monocytes, and macrophages. CD163 is up-regulated on mononuclear phagocytes by IL-4, IL-6 and dexamethasone and serves as a receptor for the hemoglobin / haptoglobin complex. Expression of CD163 is restricted to cells of monocyte lineage and increases as the monocytes mature into macrophages. CD163 is present on all CD14 + monocytes, most CD64+ monocytes, and demonstrates higher expression on CD16+ monocytes. Stimulation of monocytes and macrophages by lipopolysacharide (LPS), IL-10, and tumor necrosis factor alpha (TNF-α) causes shedding of CD163 from the cell surface into plasma or supernata

Isotyp: IgG1

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: 4 °C

Details zu CD163

Target: CD163

Andere Bezeichnung: CD163

Hintergrund: Antigen distribution: The CD163 antigen is the cysteine-rich human scavenger receptor protein (p155, M130) found on mononuclear phagocytes, monocytes, and macrophages. CD163 is up-regulated on mononuclear phagocytes by IL-4, IL-6 and dexamethasone and serves as a receptor for the hemoglobin / haptoglobin complex. Expression of CD163 is restricted to cells of monocyte lineage and increases as the monocytes mature into macrophages. CD163 is present on all CD14 + monocytes, most CD64+ monocytes, and demonstrates higher expression on CD16+ monocytes. Stimulation of monocytes and macrophages by lipopolysacharide (LPS), IL-10, and tumor necrosis factor alpha (TNF-α) causes shedding of CD163 from the cell surface into plasma or supernata. Cellular Expression: Mononuclear phagocytes, monocytes and macrophages.