CD16 Antikörper (FITC)
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- Target Alle CD16 Antikörper anzeigen
- CD16
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD16 Antikörper ist konjugiert mit FITC
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Applikation
- Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Spezifität
- B-E16 produces mouse IgG2a immunoglobulins specific for a 50-70 kD antigen which is associated with the IgG FceRI on NK cells, neutrophils, granulocytes and monocytes [3]
- Klon
- B-E16
- Isotyp
- IgG2a
- Top Product
- Discover our top product CD16 Primärantikörper
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- Applikationshinweise
- immunohistochemistry on cytospots, immunohistochemistry on frozen tissue
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Lagerung
- 4 °C
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- Target
- CD16
- Andere Bezeichnung
- CD16 (CD16 Produkte)
- Hintergrund
- Antigen distribution: CD16 is a low-affinity receptor for aggregated IgG (FcgRIII) [1,2]. The transmembrane form of CD16 is expressed on approximately 15% of peripheral blood lymphocytes and is present on virtually all resting NK cells. It is also found on macrophages and mast cells. It binds IgG complexed to antigens and mediates phagocytosis and antibody-dependent cellular cytotoxicity. On NK cells it mediates signal transduction while the GPI-linked form on neutrophils binds to ligands but is unable to induce any signal or functional effect [1]. Cellular Expression: NK cells, neutrophils, granulocytes, macrophages.
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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