Kurzübersicht für Lambda-IgLC Antikörper (Biotin) (ABIN6253019)
Target
Lambda-IgLC
(lambda Light Chain (Lambda-IgLC))
Reaktivität
Human
Wirt
Maus
Klonalität
Monoklonal
Konjugat
Dieser Lambda-IgLC Antikörper ist konjugiert mit Biotin
Applikation
Flow Cytometry (FACS)
Güteklasse
GMP Grade
Klon
HP6054
Verwendungszweck
Anti-Lambda Light Chain Biotin Antibody
Produktmerkmale
The clone HP6054 specifically binds with both soluble and membrane bound human lambda light chain of immunoglobulin but not binds with the kappa light chain or heavy chain. Lambda light chains are primarily expressed on the surface of B cells in lymphoid tissues. Each B cell expresses only one class of light chain kappa or lambda. In serum of a healthy individual, the total kappa to lambda ratio is approximately 3:1 while measuring as intact whole antibodies or 1:1.5 while measuring as free light chains. Various clinical research data claim that any highly divergent ratio of kappa to lambda indicative of neoplasm. HP6054 is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas.
Aufreinigung
Purified
Reinheit
>95 %
Immunogen
Purified human IgG myeloma proteins covalently coupled to polyaminostyrene (PAS) microbeads