FTL Antikörper (AA 38-165)

Produktnummer ABIN6252862

Der Maus Monoklonal Anti-FTL-Antikörper wurde für WB, IHC, IF und FACS validiert. Er ist geeignet, FTL in Proben von Human zu detektieren.

Kurzübersicht für FTL Antikörper (AA 38-165) (ABIN6252862)

Target: FTL (Ferritin, Light Polypeptide (FTL))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FTL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Klon: FTL-1386

Produktdetails anti-FTL Antikörper

Bindungsspezifität: AA 38-165

Aufreinigung: Protein G affinity chromatography

Immunogen: Amino acids 38-165 of human FTL were used as the immunogen for this Ferritin Light Chain antibody.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Western blot: 0.1-0.2 μg/mL

Flow Cytometry: 0.1-0.2 μg/10^6 cells

IF: 0.1-0.2 μg/mL

IHC (FFPE): 0.1-0.2 μg/mL for 30 min at RT

The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the Ferritin Light Chain antibody to be titered up or down for optimal performance.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Details zu FTL

Target: FTL (Ferritin, Light Polypeptide (FTL))

Andere Bezeichnung: FTL1

Hintergrund: Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.

Gen-ID: 2512

UniProt: P02792

Pathways: Transition Metal Ion Homeostasis