Provided assay concentrations are suggestions only, IL1RL1 antibody titration may be required for optimal results.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.5 mg/mL
Buffer
PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot and Store at -20C. Avoid freez-thaw cycles.
Target
IL1RL1
(Interleukin 1 Receptor-Like 1 (IL1RL1))
Andere Bezeichnung
IL1RL1
Hintergrund
IL1RL1 (Interleukin 1 receptor-like 1), also known as ST2 and ST2V, is a member of the IL1R family and TLR superfamily. TIR proteins initiate the innate immune response through NF-kB. Unlike other TIR proteins, IL1RL1 doesn't activate NF-kB. Instead, it promotes endotoxin tolerance through suppressive interaction with TLR4 and IL1R. This TLR inhibition also promotes a Th2 response.