HIV-1 p24 Antikörper

Produktnummer ABIN6252713

Der Maus Monoklonal anti-HIV-1 p24 Antikörper (Klon HIV1-24-661) (ABIN6252713) detektiert spezifisch HIV-1 p24 in ELISA, IF und ICC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für HIV-1 p24 Antikörper (ABIN6252713)

Target: HIV-1 p24 (Human Immunodeficiency Virus 1 Capsid (HIV-1 p24))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HIV-1 p24 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Klon: HIV1-24-661

Produktdetails anti-HIV-1 p24 Antikörper

Aufreinigung: Protein G affinity chromatography

Immunogen: Recombinant HIV-1 Gag p24 protein was used as the immunogen for this antibody.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: ELISA: order BSA-free format for coating

Immunocytochemistry (Acetone or paraformaldehyde fixed): 0.5-1 μg/mL for 30 min

IF: 0.5-1 μg/mL



The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the HIV Type-1 p24 antibody to be titered up or down for optimal performance.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Details zu HIV-1 p24

Target: HIV-1 p24 (Human Immunodeficiency Virus 1 Capsid (HIV-1 p24))

Andere Bezeichnung: HIV Type-1 p24

Substanzklasse: Viral Protein

Hintergrund: Human immunodeficiency virus (HIV) is a retrovirus that causes acquired immune deficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. HIV mainly infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages and dendritic cells. Two species of HIV infect humans: HIV-1 and HIV-2, with HIV-1 being the more virulent strain. The gag gene of human immunodeficiency virus 1 (HIV-1) encodes a precursor protein known as Pr55Gag. The viral protease PR cleaves this precursor to generate p17, p24, p7, and p6 proteins, which are required for virus particle assembly. HIV-1 Gag p24 is a capsid protein that constitutes the core of AIDS virus HIV-1. p6 and p7 are the components of the nucleocapsid, and p17 provides a protective matrix. HIV-1 Gag p24 is indispensable to the reproduction of AIDS virus and constitutes an essential element for the AIDS virus particle construction. As this protein is detectable from the early stage of AIDS virus infection, its measurement is commonly used as an indicator of HIV-1 infection and viral load.

Gen-ID: 155348