Very Low Density Lipoprotein (VLDL) (C-Term) Antikörper

Produktnummer ABIN6252626

Dieses Anti--Antikörper ist ein Mouse Monoclonal-Antikörper zur Detektion von in WB, FACS, IHC (p), IF. Geeignet für Human, Rat.

Kurzübersicht für Very Low Density Lipoprotein (VLDL) (C-Term) Antikörper (ABIN6252626)

Target: Very Low Density Lipoprotein (VLDL)

Reaktivität: Human, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Klon: VLDLR-1337

Produktdetails

Bindungsspezifität: C-Term

Aufreinigung: Protein G affinity chromatography

Immunogen: A human recombinant partial protein from the C-terminal region was used as the immunogen for this VLDL Receptor antibody.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: 0.5-1 μg/10^6 cells in 0.1ml

IF: 1-2 μg/mL

Western blot: 1-2 μg/mL

IHC (FFPE): 1-2 μg/mL for 30 min at RT

The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the VLDL Receptor antibody to be titered up or down for optimal performance.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Antigendetails

Target: Very Low Density Lipoprotein (VLDL)

Andere Bezeichnung: VLDL

Hintergrund: Very Low Density Lipoprotein Receptor (VLDLR/VLDL receptor) is a member of the LDL receptor gene family which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDL receptor is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.

Gen-ID: 7436

UniProt: P98155