HCG beta Antikörper

Produktnummer ABIN6252542

Produktdetails anti-HCG beta Antikörper

Target: HCG beta

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HCG beta Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Aufreinigung: Protein G affinity chromatography

Immunogen: Purified HCG-beta protein was used as the immunogen for this antibody.

Klon: HCGb-211

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: ELISA: use BSA-free format (1)

IHC (Frozen): 0.5-1 μg/mL for 30 min at RT

The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the HCG-beta antibody to be titered up or down for optimal performance.

1. Clone HCGb/211 (recommended capture) will pair with clones < a href=../tds/hcg-beta-antibody-hcgb459-v2373>HCGb/459 and < a href=../tds/hcg-beta-antibody-hcgb54-v2092>HCGb/54 (recommended detect) by ELISA.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Details zu HCG beta

Target: HCG beta

Andere Bezeichnung: HCG-beta (HCG beta Produkte)

Hintergrund: This antibody reacts with a protein of 22  kDa, identified as beta subunit of HCG. It does not cross react with the alpha subunit. HCG is a glycoprotein which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha and beta subunits. The alpha subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). HCG-beta antibody detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate antibody positivity in 90 % and 60 % of cases respectively, 20 % of lung squamous cell carcinomas are positive. HCG expression by non-trophoblastic tumors may indicate aggressive behavior.

Gen-ID: 1082

UniProt: Q6NT52