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Filaggrin Antikörper (AA 998-1104)

FLG Reaktivität: Human IHC, WB, IF, FACS Wirt: Maus Monoclonal FLG-1561 unconjugated
Produktnummer ABIN6252502
  • Target Alle Filaggrin (FLG) Antikörper anzeigen
    Filaggrin (FLG)
    Bindungsspezifität
    • 15
    • 10
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 998-1104
    Reaktivität
    • 64
    • 18
    • 12
    Human
    Wirt
    • 48
    • 23
    Maus
    Klonalität
    • 43
    • 28
    Monoklonal
    Konjugat
    • 42
    • 9
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Filaggrin Antikörper ist unkonjugiert
    Applikation
    • 37
    • 31
    • 24
    • 24
    • 13
    • 13
    • 9
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
    Aufreinigung
    Protein G affinity chromatography
    Immunogen
    Amino acids 998-1104 of human FLG were used as the immunogen for this Filaggrin antibody.
    Klon
    FLG-1561
    Isotyp
    IgG
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  • Applikationshinweise
    Flow Cytometry: 0.5-1 μg/10^6 cells in 0.1ml

    IF: 1-2 μg/mL

    IHC (FFPE): 0.5-1 μg/mL for 30 min at RT

    Optimal dilution of the Filaggrin antibody should be determined by the researcher.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.2 mg/mL
    Buffer
    PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot and Store at -20C. Avoid freez-thaw cycles.
  • Target
    Filaggrin (FLG)
    Andere Bezeichnung
    Filaggrin (FLG Produkte)
    Synonyme
    AW107830 antikoerper, ft antikoerper, FLG antikoerper, ATOD2 antikoerper, Pflg antikoerper, Flg antikoerper, filaggrin antikoerper, Flg antikoerper, FLG antikoerper, LOC100351762 antikoerper, LOC100728006 antikoerper
    Hintergrund
    Filaggrin (FLG) is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple Filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional Filaggrin molecules. Active Filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
    Gen-ID
    2312
    UniProt
    P20930
    Pathways
    Sensory Perception of Sound, Stem Cell Maintenance
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