LGALS1/Galectin 1 Antikörper (AA 12-108)

Produktnummer ABIN6252495

Dieses Maus Monoklonal-Antikörper erkennt spezifisch LGALS1/Galectin 1 in WB, ELISA, FACS, IF und IHC (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für LGALS1/Galectin 1 Antikörper (AA 12-108) (ABIN6252495)

Target: LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LGALS1/Galectin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: GAL1-1831

Produktdetails anti-LGALS1/Galectin 1 Antikörper

Bindungsspezifität: AA 12-108

Aufreinigung: Protein G affinity chromatography

Immunogen: A human partial recombinant protein corresponding to amino acids 12-108 was used as the immunogen for the Galectin 1 antibody.

Isotyp: IgG1 lambda

Anwendungsinformationen

Applikationshinweise: ELISA: 2-4 μg/mL, order the BSA-free formulation for coating

IF: 1-2 μg/mL

Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

WB: 0.5-1 μg/mL

IHC (FFPE): 0.5-1 μg/mL for 30 min at RT

Titering of the Galectin 1 antibody may be required for optimal performance.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Details zu LGALS1/Galectin 1

Target: LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

Andere Bezeichnung: Galectin 1

Hintergrund: Galectin 1 is a member of the beta-galactoside-binding family and is a dimeric protein of 14 kDa participating in a variety of normal and pathological processes, including cancer progression. Galectin 1 can affect the proliferation of normal and malignant cells. Inhibition of cell growth is observed in a lactose-dependent manner as lower concentrations of the lectin stimulate cell proliferation. Galectin 1 may also be implicated in the induction of apoptosis of activated T cells through the binding of exogenous galectin-1 to CD45 Molecules present on the surface of lymphocytes. Galectin 1, reported to be present either at the surface of cancer cells or accumulated around these cells could act as an immunological shield to protect against a T cell immune response and provide an advantage for survival.

Gen-ID: 3956

UniProt: P09382

Pathways: Carbohydrate Homeostasis