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FLI1 Antikörper (AA 107-216)

Dieses Maus Monoklonal-Antikörper erkennt spezifisch FLI1 in WB, IF und FACS. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN6252309

Kurzübersicht für FLI1 Antikörper (AA 107-216) (ABIN6252309)

Target

Alle FLI1 Antikörper anzeigen
FLI1 (Friend Leukemia Virus Integration 1 (FLI1))

Reaktivität

  • 76
  • 27
  • 20
  • 9
  • 6
  • 6
  • 6
  • 6
  • 5
  • 5
  • 4
  • 4
  • 4
  • 3
Human

Wirt

  • 53
  • 22
  • 1
Maus

Klonalität

  • 50
  • 26
Monoklonal

Konjugat

  • 54
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser FLI1 Antikörper ist unkonjugiert

Applikation

  • 64
  • 32
  • 26
  • 22
  • 15
  • 13
  • 9
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Klon

FLVI1-1
  • Bindungsspezifität

    • 12
    • 9
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 107-216

    Aufreinigung

    Protein G affinity chromatography

    Immunogen

    Human partial recombinant protein (amino acids 107-216) was used as the immunogen for this FLI1 antibody.

    Isotyp

    IgG
  • Applikationshinweise

    Western blot: 1-2 μg/m,l

    Flow Cytometry: 0.5-1 μg/10^6 cells

    IF: 1-2 μg/mL

    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the FLI1 antibody to be titered up or down for optimal performance.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.2 mg/mL

    Buffer

    PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Aliquot and Store at -20C. Avoid freez-thaw cycles.
  • Target

    FLI1 (Friend Leukemia Virus Integration 1 (FLI1))

    Andere Bezeichnung

    FLI1

    Hintergrund

    Friend leukemia integration 1 is a member of the ETS family of DNA binding transcription factors that is involved in cellular proliferation and tumorigenesis. Members of the Ets gene family share a highly conserved carboxy-terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. Approximately 90 % of Ewing's Sarcoma (EWS) / Primitive Neuroectodermal Tumors (PNET) have a specific translocation, t(11,22)(q24,q12), which results in fusion of EWS to Fli-1, and production of an EWS-Fli-1 fusion protein. Among normal tissues only endothelial cells and small lymphocytes express Fli-1. This protein is expressed in majority of vascular tumors including angiosarcomas, hemangioendotheliomas, hemangiomas, and Kaposi's Sarcomas. High sensitivity and specificity of Fli-1 equals to or exceeds that of the established vascular markers like CD31, CD34, and Factor VIII.

    Gen-ID

    2313

    UniProt

    Q01543
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