EPC1 Antikörper (AA 425-460)

Produktnummer ABIN6244308

Der Kaninchen Polyklonal Anti-EPC1-Antikörper wurde für WB validiert. Er ist geeignet, EPC1 in Proben von Maus zu detektieren.

Kurzübersicht für EPC1 Antikörper (AA 425-460) (ABIN6244308)

Target: EPC1 (Enhancer of Polycomb Homolog 1 (EPC1))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB51001

Produktdetails anti-EPC1 Antikörper

Bindungsspezifität: AA 425-460

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Epc1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 425-460 amino acids from the Central region of Mouse Epc1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu EPC1

Target: EPC1 (Enhancer of Polycomb Homolog 1 (EPC1))

Andere Bezeichnung: Epc1

Hintergrund: Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage (By similarity).

Molekulargewicht: 90411

UniProt: Q8C9X6

Pathways: Regulation of Muscle Cell Differentiation