Mare/Nprl3/C16orf35 Antikörper (AA 86-117)
Kurzübersicht für Mare/Nprl3/C16orf35 Antikörper (AA 86-117) (ABIN6244303)
Target
Alle Mare/Nprl3/C16orf35 (C16orf35) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 86-117
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Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This NPRL3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 86-117 amino acids from human NPRL3.
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Isotyp
- Ig Fraction
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anti-MARE (C16orf35) (AA 349-482) antibody
C16orf35 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-MARE (C16orf35) (AA 470-568) antibodyC16orf35 Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-MARE (C16orf35) (AA 470-568) antibodyC16orf35 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 4E6 unconjugated
anti-MARE (C16orf35) (Internal Region) antibodyVerified C16orf35 Reaktivität: Human WB, ELISA Wirt: Ziege Polyclonal unconjugated
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Applikationshinweise
- WB: 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Haltbarkeit
- 6 months
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- Mare/Nprl3/C16orf35 (C16orf35) (MARE (C16orf35))
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Andere Bezeichnung
- NPRL3
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Hintergrund
- As a component of the GATOR1 complex, inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC- containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling.
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Molekulargewicht
- 63605
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UniProt
- Q12980
Target
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