Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch WDR82 in WB, FACS und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Zebrafisch (Danio rerio).
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This WDR82 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 50-85 amino acids from the N-terminal region of human WDR82.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Haltbarkeit
6 months
Target
WDR82
(WD Repeat Domain 82 (WDR82))
Andere Bezeichnung
WDR82
Hintergrund
Regulatory component of the SET1 complex implicated in the tethering of this complex to transcriptional start sites of active genes. Facilitates histone H3 'Lys-4' methylation via recruitment of the SETD1A or SETD1B to the 'Ser-5' phosphorylated C-terminal domain (CTD) of RNA polymerase II large subunit (POLR2A). Component of PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.