TMEM106B Antikörper (AA 218-252)
Kurzübersicht für TMEM106B Antikörper (AA 218-252) (ABIN6244143)
Target
Alle TMEM106B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 218-252
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Homologie
- B, Rat
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Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This TMEM106B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 218-252 amino acids from human TMEM106B.
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Isotyp
- Ig Fraction
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Applikationshinweise
- WB: 1:2000. FC: 1:25
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Haltbarkeit
- 6 months
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: "Amyloid fibrils in FTLD-TDP are composed of TMEM106B and not TDP-43." in: Nature, Vol. 605, Issue 7909, pp. 304-309, (2022) (PubMed).
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- TMEM106B (Transmembrane Protein 106B (TMEM106B))
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Andere Bezeichnung
- TMEM106B
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Hintergrund
- Involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking via its interaction with MAP6. May act by inhibiting retrograde transport of lysosomes along dendrites. Required for dendrite branching.
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Molekulargewicht
- 31127
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UniProt
- Q9NUM4
Target
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