RENT1/UPF1 Antikörper (AA 583-612)
(1 reference)-
- Target Alle RENT1/UPF1 (UPF1) Antikörper anzeigen
- RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))
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Bindungsspezifität
- AA 583-612
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RENT1/UPF1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Homologie
- M
- Aufreinigung
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogen
- This RENT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 583-612 amino acids from the Central region of human RENT1.
- Klon
- RB8354
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product UPF1 Primärantikörper
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anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 270-370) antibody
UPF1 Reaktivität: Human WB, IF, IP Wirt: Kaninchen Polyclonal unconjugated
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 270-370) antibodyUPF1 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) antibodyUPF1 Reaktivität: Human, Maus WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) antibodyUPF1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 578-614), (Middle Region) antibodyUPF1 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 301-450) antibodyUPF1 Reaktivität: Human ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 7-37), (N-Term) antibodyUPF1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB8018 unconjugated
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 1019-1116) antibodyUPF1 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 4G3 unconjugated
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 956-1125) antibodyUPF1 Reaktivität: Human ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 1019-1116) antibodyUPF1 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 4G3 unconjugated
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- Applikationshinweise
- WB: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Haltbarkeit
- 6 months
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: "The intronic GABRG2 mutation, IVS6+2T->G, associated with childhood absence epilepsy altered subunit mRNA intron splicing, activated nonsense-mediated decay, and produced a stable truncated γ2 ..." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 17, pp. 5937-52, (2012) (PubMed).
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: "The intronic GABRG2 mutation, IVS6+2T->G, associated with childhood absence epilepsy altered subunit mRNA intron splicing, activated nonsense-mediated decay, and produced a stable truncated γ2 ..." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 17, pp. 5937-52, (2012) (PubMed).
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- Target
- RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))
- Andere Bezeichnung
- RENT1 (UPF1 Produkte)
- Hintergrund
- RENT1 is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping.
- Molekulargewicht
- 124345
- NCBI Accession
- NP_002902
- UniProt
- Q92900
- Pathways
- SARS-CoV-2 Protein Interaktom
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