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R-Spondin 3 Antikörper (AA 214-248)

RSPO3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB54573 unconjugated
Produktnummer ABIN6243983
  • Target Alle R-Spondin 3 (RSPO3) Antikörper anzeigen
    R-Spondin 3 (RSPO3)
    Bindungsspezifität
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 214-248
    Reaktivität
    • 23
    • 9
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 18
    • 2
    • 2
    • 2
    • 1
    Kaninchen
    Klonalität
    • 21
    • 4
    Polyklonal
    Konjugat
    • 19
    • 2
    • 2
    • 2
    Dieser R-Spondin 3 Antikörper ist unkonjugiert
    Applikation
    • 18
    • 13
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This RSPO3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 214-248 amino acids from human RSPO3.
    Klon
    RB54573
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product RSPO3 Primärantikörper
  • Applikationshinweise
    WB: 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Target
    R-Spondin 3 (RSPO3)
    Andere Bezeichnung
    RSPO3 (RSPO3 Produkte)
    Synonyme
    pwtsr antikoerper, thsd2 antikoerper, cristin1 antikoerper, CRISTIN1 antikoerper, PWTSR antikoerper, THSD2 antikoerper, RGD1563246 antikoerper, 2810459H04Rik antikoerper, AW742308 antikoerper, Cristin1 antikoerper, Thsd2 antikoerper, R-spondin 3 antikoerper, rspo3 antikoerper, RSPO3 antikoerper, Rspo3 antikoerper
    Hintergrund
    Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway.
    Molekulargewicht
    30929
    UniProt
    Q9BXY4
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