NDN Antikörper (N-Term)

Produktnummer ABIN6243906

Der Kaninchen Polyklonal Anti-NDN-Antikörper wurde für WB validiert. Er ist geeignet, NDN in Proben von Human zu detektieren.

Kurzübersicht für NDN Antikörper (N-Term) (ABIN6243906)

Target: NDN (Necdin Homolog (Mouse) (NDN))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NDN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB51025

Produktdetails anti-NDN Antikörper

Bindungsspezifität: AA 75-109, N-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NDN antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 75-109 amino acids from the N-terminal region of human NDN.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu NDN

Target: NDN (Necdin Homolog (Mouse) (NDN))

Andere Bezeichnung: NDN

Hintergrund: Growth suppressor that facilitates the entry of the cell into cell cycle arrest. Functionally similar to the retinoblastoma protein it binds to and represses the activity of cell-cycle- promoting proteins such as SV40 large T antigen, adenovirus E1A, and the transcription factor E2F. Necdin also interacts with p53 and works in an additive manner to inhibit cell growth. Functions also as transcription factor and binds directly to specific guanosine-rich DNA sequences (By similarity).

Molekulargewicht: 36086

UniProt: Q99608

Pathways: Neurotrophin Signalübertragung