CSK Antikörper (N-Term)
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- Target Alle CSK Antikörper anzeigen
- CSK (C-Src tyrosine Kinase (CSK))
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Bindungsspezifität
- AA 67-101, N-Term
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Reaktivität
- Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CSK Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Homologie
- B, H, Rat
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This Mouse Csk antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 67-101amino acids from the N-terminal region of human Mouse Csk.
- Klon
- RB50568
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product CSK Primärantikörper
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anti-C-Src tyrosine Kinase (CSK) (AA 1-100) antibody
CSK Reaktivität: Human WB, ELISA, IP, IHC (p), RNAi Wirt: Maus Monoclonal 3A3 unconjugated
anti-C-Src tyrosine Kinase (CSK) antibodyCSK Reaktivität: Human WB, ELISA, ICC, FACS Wirt: Maus Monoclonal 5F3 unconjugated
anti-C-Src tyrosine Kinase (CSK) antibodyCSK Reaktivität: Human WB, IHC Wirt: Kaninchen Monoclonal unconjugated
anti-C-Src tyrosine Kinase (CSK) (C-Term) antibodyVerified CSK Reaktivität: Human WB, ELISA Wirt: Ziege Polyclonal unconjugated
anti-C-Src tyrosine Kinase (CSK) (AA 243-438) antibodyCSK Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-C-Src tyrosine Kinase (CSK) (AA 325-416) antibodyCSK Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-C-Src tyrosine Kinase (CSK) (AA 330-450) antibodyCSK Reaktivität: Human, Maus WB, IP, ICC Wirt: Maus Monoclonal CSK-04 unconjugated
anti-C-Src tyrosine Kinase (CSK) (Ser280) antibodyCSK Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-C-Src tyrosine Kinase (CSK) (AA 241-450) antibodyCSK Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-C-Src tyrosine Kinase (CSK) (AA 1-200) antibodyCSK Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB: 1:1000. IHC-P: 1:25
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Haltbarkeit
- 6 months
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- Target
- CSK (C-Src tyrosine Kinase (CSK))
- Andere Bezeichnung
- Csk (CSK Produkte)
- Hintergrund
- Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases (SFKs) including LCK, SRC, HCK, FYN, LYN or YES1. Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation. To inhibit SFKs, CSK is recruited to the plasma membrane via binding to transmembrane proteins or adapter proteins located near the plasma membrane. Suppresses signaling by various surface receptors, including T- cell receptor (TCR) and B-cell receptor (BCR) by phosphorylating and maintaining inactive several positive effectors such as FYN or LCK (By similarity).
- Molekulargewicht
- 50716
- UniProt
- P41241
- Pathways
- T-Zell Rezeptor Signalweg, EGFR Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events
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