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CSK Antikörper (N-Term)

Name: CSK Antikörper (N-Term)
SKU: ABIN6243612
Price: 434.77 EUR
Availability: InStock

CSK Reaktivität: Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB50568 unconjugated

Western blot analysis of lysate from mouse liver tissue lysate, using Mouse Csk Antibody (N-term) (ABIN6243612 and ABIN6577562). (CSK Antikörper (N-Term))

Immunohistochemical analysis of paraffin-embedded M. (CSK Antikörper (N-Term))

IHC (p)

2 Abbildungen

Produktnummer ABIN6243612

Datenblatt (PDF)

Target Alle CSK Antikörper anzeigen

CSK (C-Src tyrosine Kinase (CSK))
Bindungsspezifität
16

15

8

8

7

6

5

4

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 67-101, N-Term
Reaktivität
97

52

43

3

3

2

2

2

1

1
Maus
Wirt
86

10

2
Kaninchen
Passende Sekundärantikörper
Klonalität
83

14
Polyklonal
Konjugat
49

7

6

5

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1
Dieser CSK Antikörper ist unkonjugiert
Applikation
87

36

24

24

16

15

12

9

7

6

6

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie

B, H, Rat

Aufreinigung

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen

This Mouse Csk antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 67-101amino acids from the N-terminal region of human Mouse Csk.

Klon

RB50568

Isotyp

Ig Fraction

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CSK Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated

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CSK Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-C-Src tyrosine Kinase (CSK) (AA 1-200) antibody
CSK Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated

anti-C-Src tyrosine Kinase (CSK) (AA 1-156) antibody
CSK Reaktivität: Human, Maus, Ratte, Huhn, Hund WB, IHC, IF, IP Wirt: Maus Monoclonal 52-Csk unconjugated

anti-C-Src tyrosine Kinase (CSK) (AA 2-204) antibody
CSK Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB: 1:1000. IHC-P: 1:25

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Haltbarkeit

6 months
Target

CSK (C-Src tyrosine Kinase (CSK))

Andere Bezeichnung

Csk (CSK Produkte)

Hintergrund

Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases (SFKs) including LCK, SRC, HCK, FYN, LYN or YES1. Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation. To inhibit SFKs, CSK is recruited to the plasma membrane via binding to transmembrane proteins or adapter proteins located near the plasma membrane. Suppresses signaling by various surface receptors, including T- cell receptor (TCR) and B-cell receptor (BCR) by phosphorylating and maintaining inactive several positive effectors such as FYN or LCK (By similarity).

Molekulargewicht

50716

UniProt

P41241

Pathways

T-Zell Rezeptor Signalweg, EGFR Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events