GAPDHS Antikörper (AA 104-134)

Produktnummer ABIN6243346

Zitiert in 2+ Publikationen. Der Kaninchen Polyklonal anti-GAPDHS Antikörper (Klon RB16542) (ABIN6243346) detektiert spezifisch GAPDHS in WB, IHC (p) und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für GAPDHS Antikörper (AA 104-134) (ABIN6243346)

Target: GAPDHS (Glyceraldehyde-3-Phosphate Dehydrogenase, Spermatogenic (GAPDHS))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GAPDHS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Klon: RB16542

Produktdetails anti-GAPDHS Antikörper

Bindungsspezifität: AA 104-134

Homologie: Pr

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This GAPDHS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-134 amino acids from the Central region of human GAPDHS.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-GAPDHS Antikörper (ABIN6243346)

Maselli, Hales, Robaire: "The effects of chemotherapy with bleomycin, etoposide, and cis-platinum (BEP) on rat sperm chromatin remodeling, fecundity and testicular gene expression in the progeny." in: Biology of reproduction, Vol. 89, Issue 4, pp. 85, (2014) (PubMed).

Maselli, Hales, Chan, Robaire: "Exposure to bleomycin, etoposide, and cis-platinum alters rat sperm chromatin integrity and sperm head protein profile." in: Biology of reproduction, Vol. 86, Issue 5, pp. 166, 1-10, (2012) (PubMed).

Details zu GAPDHS

Target: GAPDHS (Glyceraldehyde-3-Phosphate Dehydrogenase, Spermatogenic (GAPDHS))

Andere Bezeichnung: GAPDHS

Hintergrund: GAPDHS is a protein belonging to the glyceraldehyde-3-phosphate dehydrogenase family of enzymes that play an important role in carbohydrate metabolism. Like its somatic cell counterpart, this sperm-specific enzyme functions in a nicotinamide adenine dinucleotide-dependent manner to remove hydrogen and add phosphate to glyceraldehyde 3-phosphate to form 1,3-diphosphoglycerate. During spermiogenesis, this enzyme may play an important role in regulating the switch between different energy-producing pathways, and it is required for sperm motility and male fertility.

Molekulargewicht: 44501

NCBI Accession: NP_055179

UniProt: O14556

Pathways: Regulation of Carbohydrate Metabolic Process