Znf423 Antikörper (AA 864-897)

Produktnummer ABIN6243344

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Znf423 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Znf423 Antikörper (AA 864-897) (ABIN6243344)

Target: Znf423 (Zinc Finger Protein 423 (Znf423))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Znf423 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB49865

Produktdetails anti-Znf423 Antikörper

Bindungsspezifität: AA 864-897

Homologie: M, Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ZNF423 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 864-897 amino acids from the Central region of human ZNF423.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu Znf423

Target: Znf423 (Zinc Finger Protein 423 (Znf423))

Andere Bezeichnung: ZNF423

Hintergrund: Transcription factor that can both act as an activator or a repressor depending on the context. Plays a central role in BMP signaling and olfactory neurogenesis. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation, this interaction preventing EBF1 to bind DNA and activate olfactory-specific genes. Involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons. Controls proliferation and differentiation of neural precursors in cerebellar vermis formation.

Molekulargewicht: 144605

UniProt: Q2M1K9