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Znf423 Antikörper (AA 864-897)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Znf423 in WB. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN6243344

Kurzübersicht für Znf423 Antikörper (AA 864-897) (ABIN6243344)

Target

Alle Znf423 Antikörper anzeigen
Znf423 (Zinc Finger Protein 423 (Znf423))

Reaktivität

  • 16
  • 10
  • 8
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Human

Wirt

  • 15
  • 3
  • 1
Kaninchen

Klonalität

  • 16
  • 3
Polyklonal

Konjugat

  • 14
  • 2
  • 2
  • 1
Dieser Znf423 Antikörper ist unkonjugiert

Applikation

  • 12
  • 6
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)

Klon

RB49865
  • Bindungsspezifität

    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 864-897

    Homologie

    M, Rat

    Aufreinigung

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogen

    This ZNF423 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 864-897 amino acids from the Central region of human ZNF423.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    WB: 1:1000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Haltbarkeit

    6 months
  • Target

    Znf423 (Zinc Finger Protein 423 (Znf423))

    Andere Bezeichnung

    ZNF423

    Hintergrund

    Transcription factor that can both act as an activator or a repressor depending on the context. Plays a central role in BMP signaling and olfactory neurogenesis. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation, this interaction preventing EBF1 to bind DNA and activate olfactory-specific genes. Involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons. Controls proliferation and differentiation of neural precursors in cerebellar vermis formation.

    Molekulargewicht

    144605

    UniProt

    Q2M1K9
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