SOX2 Antikörper (C-Term)
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- Target Alle SOX2 Antikörper anzeigen
- SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
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Bindungsspezifität
- AA 282-316, C-Term
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SOX2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Homologie
- C, Sh
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This SOX2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 282-316 amino acids from the C-terminal region of human SOX2.
- Klon
- RB51412
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product SOX2 Primärantikörper
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- Applikationshinweise
- WB: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Haltbarkeit
- 6 months
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- Target
- SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
- Andere Bezeichnung
- SOX2 (SOX2 Produkte)
- Hintergrund
- Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).
- Molekulargewicht
- 34310
- UniProt
- P48431
- Pathways
- Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
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