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RUNX2 Antikörper (N-Term)

Dieses Anti-RUNX2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RUNX2 in IHC (p). Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.
Produktnummer ABIN6243280

Kurzübersicht für RUNX2 Antikörper (N-Term) (ABIN6243280)

Target

Alle RUNX2 Antikörper anzeigen
RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

Reaktivität

  • 127
  • 58
  • 33
  • 10
  • 9
  • 8
  • 8
  • 8
  • 7
  • 5
  • 5
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 122
  • 13
Kaninchen

Klonalität

  • 113
  • 22
Polyklonal

Konjugat

  • 70
  • 9
  • 6
  • 6
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Dieser RUNX2 Antikörper ist unkonjugiert

Applikation

  • 104
  • 50
  • 35
  • 31
  • 16
  • 14
  • 12
  • 9
  • 7
  • 3
  • 2
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

RB10543
  • Bindungsspezifität

    • 16
    • 16
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term

    Aufreinigung

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogen

    This RUNX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1~30 amino acids from the N-terminal region of human RUNX2.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    IHC-P: 1:10~50

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Haltbarkeit

    6 months
  • Ushijima, Okazaki, Tsushima, Iwamoto: "CCAAT/enhancer-binding protein β regulates the repression of type II collagen expression during the differentiation from proliferative to hypertrophic chondrocytes." in: The Journal of biological chemistry, Vol. 289, Issue 5, pp. 2852-63, (2014) (PubMed).

  • Target

    RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

    Andere Bezeichnung

    RUNX2

    Hintergrund

    Runx2 is a member of the RUNX family of transcription factors. It is a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. It can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in the Runx2 gene have been associated with the bone development disorder cleidocranial dysplasia (CCD).

    Molekulargewicht

    56648

    NCBI Accession

    NP_001015051, NP_001019801

    UniProt

    Q13950
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