DAXX Antikörper (AA 473-502)

Produktnummer ABIN6243150

Der Kaninchen Polyklonal Anti-DAXX-Antikörper wurde für WB validiert. Er ist geeignet, DAXX in Proben von Human zu detektieren.

Kurzübersicht für DAXX Antikörper (AA 473-502) (ABIN6243150)

Target: DAXX (Death-Domain Associated Protein (DAXX))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DAXX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB6869

Produktdetails anti-DAXX Antikörper

Bindungsspezifität: AA 473-502

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DAXX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 473-502 amino acids from human DAXX.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu DAXX

Target: DAXX (Death-Domain Associated Protein (DAXX))

Andere Bezeichnung: DAXX

Hintergrund: DAXX is a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, this protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, this protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination.

Molekulargewicht: 81373

NCBI Accession: NP_001135441, NP_001241646, NP_001341

UniProt: Q9UER7

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway