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DAXX Antikörper (AA 473-502)

Der Kaninchen Polyklonal Anti-DAXX-Antikörper wurde für WB validiert. Er ist geeignet, DAXX in Proben von Human zu detektieren.
Produktnummer ABIN6243150

Kurzübersicht für DAXX Antikörper (AA 473-502) (ABIN6243150)

Target

Alle DAXX Antikörper anzeigen
DAXX (Death-Domain Associated Protein (DAXX))

Reaktivität

  • 159
  • 62
  • 51
  • 7
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 142
  • 18
Kaninchen

Klonalität

  • 131
  • 29
Polyklonal

Konjugat

  • 62
  • 7
  • 7
  • 7
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
Dieser DAXX Antikörper ist unkonjugiert

Applikation

  • 131
  • 65
  • 65
  • 38
  • 37
  • 25
  • 21
  • 20
  • 16
  • 15
  • 7
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB)

Klon

RB6869
  • Bindungsspezifität

    • 23
    • 21
    • 16
    • 16
    • 15
    • 9
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 473-502

    Aufreinigung

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogen

    This DAXX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 473-502 amino acids from human DAXX.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    WB: 1:1000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Haltbarkeit

    6 months
  • Target

    DAXX (Death-Domain Associated Protein (DAXX))

    Andere Bezeichnung

    DAXX

    Hintergrund

    DAXX is a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, this protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, this protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination.

    Molekulargewicht

    81373

    NCBI Accession

    NP_001135441, NP_001241646, NP_001341

    UniProt

    Q9UER7

    Pathways

    Intracellular Steroid Hormone Receptor Signaling Pathway
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