This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This APLP1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 505-539 amino acids from the human region of human APLP1.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Haltbarkeit
6 months
Target
APLP1
(Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))
Andere Bezeichnung
APLP1
Hintergrund
May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity). Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I.