WNK1 Antikörper (AA 1848-1882)
Kurzübersicht für WNK1 Antikörper (AA 1848-1882) (ABIN6242959)
Target
Alle WNK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1848-1882
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Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This WNK1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1848-1882 amino acids from human WNK1.
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Isotyp
- IgG
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anti-WNK Lysine Deficient Protein Kinase 1 (WNK1) (pThr60) antibody
WNK1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-WNK Lysine Deficient Protein Kinase 1 (WNK1) (AA 1-207) antibodyWNK1 Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-WNK Lysine Deficient Protein Kinase 1 (WNK1) (N-Term) antibodyWNK1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-WNK Lysine Deficient Protein Kinase 1 (WNK1) (AA 1154-1195), (Middle Region) antibodyWNK1 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-WNK Lysine Deficient Protein Kinase 1 (WNK1) (AA 1954-2231) antibodyWNK1 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-WNK Lysine Deficient Protein Kinase 1 (WNK1) (AA 1-210) antibodyWNK1 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-WNK Lysine Deficient Protein Kinase 1 (WNK1) (C-Term) antibodyWNK1 Reaktivität: Human, Maus, Ratte, Pferd, Affe, Kaninchen, Fledermaus, Hamster IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-WNK Lysine Deficient Protein Kinase 1 (WNK1) (Internal Region) antibodyWNK1 Reaktivität: Human, Maus, Ratte, Pferd, Affe, Kaninchen, Schwein, Fledermaus, Hamster, Huhn, Rind (Kuh) ELISA, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-WNK Lysine Deficient Protein Kinase 1 (WNK1) (pThr60) antibodyWNK1 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-WNK Lysine Deficient Protein Kinase 1 (WNK1) (Tyr773) antibodyWNK1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB: 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Haltbarkeit
- 6 months
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- WNK1 (WNK Lysine Deficient Protein Kinase 1 (WNK1))
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Andere Bezeichnung
- WNK1
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Hintergrund
- Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A, SCNN1B, SCNN1D and SGK1. Controls sodium and chloride ion transport by inhibiting the activity of WNK4, by either phosphorylating the kinase or via an interaction between WNK4 and the autoinhibitory domain of WNK1. WNK4 regulates the activity of the thiazide- sensitive Na-Cl cotransporter, SLC12A3, by phosphorylation. WNK1 may also play a role in actin cytoskeletal reorganization. Phosphorylates NEDD4L.
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Molekulargewicht
- 250794
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UniProt
- Q9H4A3
Target
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