GNMT Antikörper (C-Term)

Produktnummer ABIN6242958

Der Kaninchen Polyklonal Anti-GNMT-Antikörper wurde für WB validiert. Er ist geeignet, GNMT in Proben von Human zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für GNMT Antikörper (C-Term) (ABIN6242958)

Target: GNMT (Glycine N-Methyltransferase (GNMT))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GNMT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB5760

Produktdetails anti-GNMT Antikörper

Bindungsspezifität: AA 218-248, C-Term

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This GNMT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-248 amino acids from the C-terminal region of human GNMT.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-GNMT Antikörper (ABIN6242958)

Wagner, Choi, Panzitt, Mamrosh, Lee, Zaufel, Xiao, Wooton-Kee, Ståhlman, Newgard, Borén, Moore: "Liver receptor homolog-1 is a critical determinant of methyl-pool metabolism." in: Hepatology (Baltimore, Md.), Vol. 63, Issue 1, pp. 95-106, (2016) (PubMed).

DiBello, Dayal, Kaveti, Zhang, Kinter, Lentz, Jacobsen: "The nutrigenetics of hyperhomocysteinemia: quantitative proteomics reveals differences in the methionine cycle enzymes of gene-induced versus diet-induced hyperhomocysteinemia." in: Molecular & cellular proteomics : MCP, Vol. 9, Issue 3, pp. 471-85, (2010) (PubMed).

Details zu GNMT

Target: GNMT (Glycine N-Methyltransferase (GNMT))

Andere Bezeichnung: GNMT

Hintergrund: Glycine N-methyltransferase catalyzes the synthesis of N-methylglycine (sarcosine) from glycine using S-adenosylmethionine (AdoMet) as the methyl donor. GNMT acts as an enzyme to regulate the ratio of S-adenosylmethionine to S-adenosylhomocysteine (AdoHcy) and participates in the detoxification pathway in liver cells.

Molekulargewicht: 32742

NCBI Accession: NP_061833

UniProt: Q14749

Pathways: Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process