Es sind 2+ Publikationen für dieses Produkt verfügbar. Der Kaninchen Polyklonal anti-GNMT Antikörper wird verwendet zum Nachweis von GNMT in Proben von Human. Er wurde validiert für WB.
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This GNMT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-248 amino acids from the C-terminal region of human GNMT.
GNMT
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
RB36190
unconjugated
Applikationshinweise
WB: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Haltbarkeit
6 months
Wagner, Choi, Panzitt, Mamrosh, Lee, Zaufel, Xiao, Wooton-Kee, Ståhlman, Newgard, Borén, Moore: "Liver receptor homolog-1 is a critical determinant of methyl-pool metabolism." in: Hepatology (Baltimore, Md.), Vol. 63, Issue 1, pp. 95-106, (2016) (PubMed).
DiBello, Dayal, Kaveti, Zhang, Kinter, Lentz, Jacobsen: "The nutrigenetics of hyperhomocysteinemia: quantitative proteomics reveals differences in the methionine cycle enzymes of gene-induced versus diet-induced hyperhomocysteinemia." in: Molecular & cellular proteomics : MCP, Vol. 9, Issue 3, pp. 471-85, (2010) (PubMed).
Target
GNMT
(Glycine N-Methyltransferase (GNMT))
Andere Bezeichnung
GNMT
Hintergrund
Glycine N-methyltransferase catalyzes the synthesis of N-methylglycine (sarcosine) from glycine using S-adenosylmethionine (AdoMet) as the methyl donor. GNMT acts as an enzyme to regulate the ratio of S-adenosylmethionine to S-adenosylhomocysteine (AdoHcy) and participates in the detoxification pathway in liver cells.