Reticulon 4 Antikörper (AA 28-58)
Kurzübersicht für Reticulon 4 Antikörper (AA 28-58) (ABIN6242947)
Target
Alle Reticulon 4 (RTN4) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 28-58
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Homologie
- M, Rat
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Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This RTN4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 28-58 amino acids from human RTN4.
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Isotyp
- Ig Fraction
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anti-Reticulon 4 (RTN4) (AA 501-515) antibody
RTN4 Reaktivität: Human, Affe IHC, IHC (p) Wirt: Ziege Polyclonal unconjugated
anti-Reticulon 4 (RTN4) (AA 14-30) antibodyRTN4 Reaktivität: Human, Maus, Ratte, Affe, Schwein WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Reticulon 4 (RTN4) (AA 301-400) antibodyRTN4 Reaktivität: Human, Ratte WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Reticulon 4 (RTN4) (AA 251-357) antibodyRTN4 Reaktivität: Human, Maus WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Reticulon 4 (RTN4) (AA 81-130) antibodyRTN4 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Schaf, Affe, Pferd, Meerschweinchen, Schwein, Fledermaus WB Wirt: Kaninchen Polyclonal unconjugated
anti-Reticulon 4 (RTN4) (AA 254-303) antibodyRTN4 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Schaf, Affe, Pferd, Schwein, Fledermaus, Huhn WB Wirt: Kaninchen Polyclonal unconjugated
anti-Reticulon 4 (RTN4) (Center) antibodyRTN4 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Schaf, Affe WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Reticulon 4 (RTN4) (Middle Region) antibodyRTN4 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Schaf, Pferd, Meerschweinchen, Schwein, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
anti-Reticulon 4 (RTN4) (N-Term) antibodyRTN4 Reaktivität: Human, Maus, Ratte WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB: 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Haltbarkeit
- 6 months
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- Reticulon 4 (RTN4)
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Andere Bezeichnung
- RTN4
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Hintergrund
- Developmental neurite growth regulatory factor with a role as a negative regulator of axon-axon adhesion and growth, and as a facilitator of neurite branching. Regulates neurite fasciculation, branching and extension in the developing nervous system. Involved in down-regulation of growth, stabilization of wiring and restriction of plasticity in the adult CNS. Regulates the radial migration of cortical neurons via an RTN4R-LINGO1 containing receptor complex (By similarity). Isoform 2 reduces the anti-apoptotic activity of Bcl-xl and Bcl-2. This is likely consecutive to their change in subcellular location, from the mitochondria to the endoplasmic reticulum, after binding and sequestration. Isoform 2 and isoform 3 inhibit BACE1 activity and amyloid precursor protein processing.
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Molekulargewicht
- 129931
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UniProt
- Q9NQC3
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Pathways
- Neurotrophin Signalübertragung, Regulation of Cell Size, SARS-CoV-2 Protein Interaktom
Target
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