LECT1 Antikörper (N-Term)

Produktnummer ABIN6242902

Dieses Anti-LECT1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von LECT1 in WB. Geeignet für Human, Maus und Ratte.

Kurzübersicht für LECT1 Antikörper (N-Term) (ABIN6242902)

Target: LECT1 (Leukocyte Cell Derived Chemotaxin 1 (LECT1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LECT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB15072

Produktdetails anti-LECT1 Antikörper

Bindungsspezifität: AA 1-30, N-Term

Homologie: B, Rb

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This LECT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human LECT1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu LECT1

Target: LECT1 (Leukocyte Cell Derived Chemotaxin 1 (LECT1))

Andere Bezeichnung: LECT1

Hintergrund: LECT1 is a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This protein expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development.

Molekulargewicht: 37102

NCBI Accession: NP_001011705, NP_008946

UniProt: O75829