Rabenosyn 5 Antikörper (AA 41-65)

Produktnummer ABIN6242883

Produktdetails anti-Rabenosyn 5 Antikörper

Target: Rabenosyn 5 (ZFYVE20) (Zinc Finger, FYVE Domain Containing 20 (ZFYVE20))

Bindungsspezifität: AA 41-65

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Rabenosyn 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ZFYVE20 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 41-65 amino acids from the human region of human ZFYVE20.

Klon: RB52910

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:8000. WB: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu Rabenosyn 5

Target: Rabenosyn 5 (ZFYVE20) (Zinc Finger, FYVE Domain Containing 20 (ZFYVE20))

Andere Bezeichnung: ZFYVE20 (ZFYVE20 Produkte)

Synonyme: zfyve20 antikoerper, Rabenosyn-5 antikoerper, 5330426D11Rik antikoerper, rabenosyn, RAB effector antikoerper, si:dkey-187a12.4 antikoerper, rabenosyn-5 antikoerper, RBSN antikoerper, si:dkey-187a12.4 antikoerper, CpipJ_CPIJ003819 antikoerper, rbsn antikoerper, Rbsn antikoerper

Hintergrund: Rab4/Rab5 effector protein acting in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathrin coated vesicles. Plays a role in the lysosomal trafficking of CTSD/cathepsin D from the Golgi to lysosomes. Also promotes the recycling of transferrin directly from early endosomes to the plasma membrane. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate (PtdInsP3) (PubMed:< a href="http://www.uniprot.org/citations/11062261" target="_blank">11062261, PubMed:< a href="http://www.uniprot.org/citations/11788822" target="_blank">11788822, PubMed:< a href="http://www.uniprot.org/citations/15020713" target="_blank">15020713). Plays a role in the recycling of transferrin receptor to the plasma membrane (PubMed:< a href="http://www.uniprot.org/citations/22308388" target="_blank">22308388).

Molekulargewicht: 88870

UniProt: Q9H1K0

Pathways: Toll-Like Receptors Cascades