Rabenosyn 5 Antikörper (AA 41-65)
Kurzübersicht für Rabenosyn 5 Antikörper (AA 41-65) (ABIN6242883)
Target
Alle Rabenosyn 5 (ZFYVE20) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 41-65
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Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This ZFYVE20 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 41-65 amino acids from the human region of human ZFYVE20.
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Isotyp
- Ig Fraction
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Applikationshinweise
- WB: 1:8000. WB: 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Haltbarkeit
- 6 months
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- Rabenosyn 5 (ZFYVE20) (Zinc Finger, FYVE Domain Containing 20 (ZFYVE20))
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Andere Bezeichnung
- ZFYVE20
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Hintergrund
- Rab4/Rab5 effector protein acting in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathrin coated vesicles. Plays a role in the lysosomal trafficking of CTSD/cathepsin D from the Golgi to lysosomes. Also promotes the recycling of transferrin directly from early endosomes to the plasma membrane. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate (PtdInsP3) (PubMed:< a href="http://www.uniprot.org/citations/11062261" target="_blank">11062261, PubMed:< a href="http://www.uniprot.org/citations/11788822" target="_blank">11788822, PubMed:< a href="http://www.uniprot.org/citations/15020713" target="_blank">15020713). Plays a role in the recycling of transferrin receptor to the plasma membrane (PubMed:< a href="http://www.uniprot.org/citations/22308388" target="_blank">22308388).
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Molekulargewicht
- 88870
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UniProt
- Q9H1K0
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Pathways
- Toll-Like Receptors Cascades
Target
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