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PI4KB Antikörper (N-Term)

PI4KB Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB1676 unconjugated
Produktnummer ABIN6242814
  • Target Alle PI4KB Antikörper anzeigen
    PI4KB (Phosphatidylinositol 4-Kinase, Catalytic, beta (PI4KB))
    Bindungsspezifität
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 20-51, N-Term
    Reaktivität
    • 23
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 21
    • 2
    Kaninchen
    Klonalität
    • 21
    • 2
    Polyklonal
    Konjugat
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PI4KB Antikörper ist unkonjugiert
    Applikation
    • 14
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    B, M, Rat
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This PI4KCB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-51 amino acids from the N-terminal region of human PI4KCB.
    Klon
    RB1676
    Isotyp
    Ig Fraction
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:50~100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Spickler, Lippens, Laberge, Desmeules, Bellavance, Garneau, Guo, Hucke, Leyssen, Neyts, Vaillancourt, Décor, OMeara, Franti, Gauthier: "Phosphatidylinositol 4-kinase III beta is essential for replication of human rhinovirus and its inhibition causes a lethal phenotype in vivo." in: Antimicrobial agents and chemotherapy, Vol. 57, Issue 7, pp. 3358-68, (2013) (PubMed).

  • Target
    PI4KB (Phosphatidylinositol 4-Kinase, Catalytic, beta (PI4KB))
    Andere Bezeichnung
    PI4KCB (PI4KB Produkte)
    Synonyme
    PIK4CB antikoerper, NV15725 antikoerper, PI4K-beta antikoerper, PI4Kbeta antikoerper, pik4cb antikoerper, NPIK antikoerper, PI4K-BETA antikoerper, PI4K92 antikoerper, PI4KBETA antikoerper, PI4KIIIBETA antikoerper, Pik4cb antikoerper, zgc:152715 antikoerper, AA437822 antikoerper, ESTM41 antikoerper, phosphatidylinositol 4-kinase, catalytic, beta antikoerper, phosphatidylinositol 4-kinase beta antikoerper, phosphatidylinositol 4-kinase, catalytic, beta L homeolog antikoerper, PI4KB antikoerper, LOC100115953 antikoerper, pi4kb antikoerper, Pi4kb antikoerper, pi4kb.L antikoerper
    Hintergrund
    Phosphoinositides are pivotal precursors to important second messengers and as signaling and molecules. Phosphatidylinositol 4-kinases (PI4Ks) are are crucial regulators of the phosphoinsitide cascade. PI4KCB is a wortmannin-sensitive PI 4-kinase responsible for regulating the synthesis of agonist-sensitive pools of polyphosphoinositides. The cellular reservoir of PI4KCB is predominantly cytosolic, however the protein is is activated strongly by recruitment to the membrane to stimulate phosphatidylinositol 4,5-bisphosphate synthesis at the plasma membrane. PI4KCB contains an N-terminal lipid kinase unique domain, which is shared by members of both the PI3 kinase and PI4 kinase families, and a C-terminal catalytic domain, which defines this protein as a member of a much larger protein/lipid kinase family.
    Molekulargewicht
    91379
    NCBI Accession
    NP_001185702, NP_001185703, NP_001185704, NP_002642
    UniProt
    Q9UBF8
    Pathways
    Inositol Metabolic Process
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