ZKSCAN3 Antikörper (AA 100-130)
Kurzübersicht für ZKSCAN3 Antikörper (AA 100-130) (ABIN6242712)
Target
Alle ZKSCAN3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 100-130
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Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This ZKSCAN3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 100-130 amino acids from human ZKSCAN3.
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Isotyp
- Ig Fraction
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Applikationshinweise
- WB: 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Haltbarkeit
- 6 months
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- ZKSCAN3 (Zinc Finger Protein 306 (ZKSCAN3))
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Andere Bezeichnung
- ZKSCAN3
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Hintergrund
- Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migation in various tumors and myelomas.
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Molekulargewicht
- 60641
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UniProt
- Q9BRR0
Target
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