Tetraspanin 6 Antikörper (C-Term)

Produktnummer ABIN6242668

Dieses Anti-Tetraspanin 6-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Tetraspanin 6 in WB und FACS. Geeignet für Human und Maus. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für Tetraspanin 6 Antikörper (C-Term) (ABIN6242668)

Target: Tetraspanin 6 (TSPAN6)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Tetraspanin 6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Klon: RB23234

Produktdetails anti-Tetraspanin 6 Antikörper

Bindungsspezifität: AA 176-205, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TSPAN6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176~205 amino acids from the C-terminal region of human TSPAN6.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-Tetraspanin 6 Antikörper (ABIN6242668)

Salas, Callaerts-Vegh, Arranz, Guix, DHooge, Esteban, De Strooper, Dotti: "Tetraspanin 6: A novel regulator of hippocampal synaptic transmission and long term plasticity." in: PLoS ONE, Vol. 12, Issue 2, pp. e0171968, (2017) (PubMed).

Guix, Sannerud, Berditchevski, Arranz, Horré, Snellinx, Thathiah, Saido, Saito, Rajesh, Overduin, Kumar-Singh, Radaelli, Corthout, Colombelli, Tosi, Munck, Salas, Annaert, De Strooper: "Tetraspanin 6: a pivotal protein of the multiple vesicular body determining exosome release and lysosomal degradation of amyloid precursor protein fragments." in: Molecular neurodegeneration, Vol. 12, Issue 1, pp. 25, (2017) (PubMed).

Details zu Tetraspanin 6

Target: Tetraspanin 6 (TSPAN6)

Andere Bezeichnung: TSPAN6

Hintergrund: The protein is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2.

Molekulargewicht: 27563

NCBI Accession: NP_001265672, NP_003261

UniProt: O43657